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2 edition of Heavy metals in the hippocampal region found in the catalog.

Heavy metals in the hippocampal region

Gorm Danscher

Heavy metals in the hippocampal region

Some aspects of localization, function and content with special emphasis on the effect ofchelating agents.

by Gorm Danscher

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  • 26 Currently reading

Published by University of Aarhus. Institute of Anatomy B in Aarhus .
Written in English


The Physical Object
Pagination36 s
Number of Pages36
ID Numbers
Open LibraryOL20993341M

Seress,L.,andToth,K.().Extracellular chelation of zinc does not affect hippocampal excitability and seizure-induced cell death in rats. (). Silencing of ZnT-1 expression enhances heavy metal influx and toxicity. (). Silencing of ZnT1 reduces Zn2+efflux in cultured cortical neurons. ().Author: Carlos Sindreu and Daniel R. Storm.   This hippocampal region is particularly vulnerable to injuries caused by ethanol consumption ultimately leading to neuronal death (Andrade et al., ; Paula-Barbosa et al., ; Lukoyanov et al., ). Thus, using unbiased stereological methods, we verified whether the different treatments affected the volumes of DG layers, the total number Cited by: 8. Heavy Industry & Manufacturing. "These EEG findings show that the hippocampal region is, indeed, where a significant change in brain wave activity is taking place in patients on active therapy. Search term. Advanced Search Citation Search. Search termCited by:

Define hippocampal. hippocampal synonyms, hippocampal pronunciation, hippocampal translation, English dictionary definition of hippocampal. n. pl. hippocampi g: Heavy metals.


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Heavy metals in the hippocampal region by Gorm Danscher Download PDF EPUB FB2

Distribution of heavy metals in the hippocampal region of the guinea pig. Summary. With the present modification of Timm's sulfide silver method all parts of the hippocampal region show a distinctly stratified staining pattern, suggesting large regional differences in the content of heavy by: Distribution of heavy metals in the hippocampal region of the guinea pig Geneser-Jensen, Finn; Haug, Finn-Mogens; Danscher, Gorm With the present modification of Timm's sulfide silver method all parts of the hippocampal region show a distinctly stratified staining pattern, suggesting large regional differences in the content of heavy metals.

The stain is largely confined to distinct. Distribution of heavy metals in the hippocampal region of the guinea pig. A light microscope study with Timm's sulfide silver method. Geneser-Jensen FA, Haug FM, Danscher by: Distribution of heavy metals in the hippocampal region of the guinea pig.

A light microscope study with Timm's sulfide silver method. 1 Find the latest peer-reviewed research articles and preprints on Coronavirus here. Braht Research, () ~f) Elsevier Scientific Publishing Company, Amsterdam - Prmted in The Netherlands Heavy metal content in subdivisions of the rat hippocampus (zinc, lead and copper) G.

DANSCHER, E. FJERDINGSTAD, E. FJERD1NGSTAD and K. FREDENS Institute Of Anatomy, University of Aarhus, Aarhus and (E.F.) Institute of Hygiene Cited by:   Lead (Pb) is a non-essential heavy metal and a ubiquitously present pollutant in the ecosystem.

In humans, inhalation and oral ingestion are the major routes of Pb exposure. In the body, Pb can be excreted in urine and bile, and some Pb can bind to red blood cells Cited by: A variety of different cytoarchitectonic and chemoarchitectonic characteristics have been used to delineate the various divisions that make up the hippocampal region, including stains for heavy metals, in particular zinc (Timm stain, acetylcholinesterase (Slomianka and West,Slomianka and Geneser, a, Slomianka and Geneser, b Cited by: 9.

Vanadium treatments for 3–18 months resulted in astrocytic activation in the dorsal hippocampal CA1 region and genu of corpus callosum. GFAP immunoreactive cells displayed thickened cell body with more extensive cytoplasmic processes in the vanadium exposed groups (Figures 2, 3B,E,H) relative to the age matched controls (Figures 2, 3A,D,G) while the withdrawal groups (Figures 2, 3C,F,I Cited by: Psy Learning: Generalization & Discrimination study guide by jessica_andrea includes 27 questions covering vocabulary, terms and more.

Quizlet flashcards, Missing: Heavy metals. #N#Core Lab > Contouring Atlases > Hippocampal Sparing. RTOG Hippocampal g: Heavy metals. The Hippocampal Formation of the Primate Brain.

A Review of Some Comparative Aspects of Cytoarchitecture and Connections T. W.,Commissural connections of the hippocampal region in the cat, with special reference to F.-M. S.,Heavy metals in the brain.

A light microscope study of the rat with Timm’s sulphide silver method Cited by:   Mnemonic information is processed in the hippocampus through several parallel routes involving distinct subregions.

In the classic trisynaptic pathway, information proceeds from entorhinal cortex (EC) to dentate gyrus to CA3 and then to CA1, the main hippocampal output. Genetic lesions Missing: Heavy metals. Heavy metals in the hippocampal region: Some aspects of localization, function and content with special emphasis on the effect of chelating agents.

Thesis, (). Importance of zinc in the central nervous system: the zinc-containing neuron. Heavy metals were found to be accumulated particularly in longitudinal muscles of animals.

CAT activity was found to be increased in animals from three of the experimental sites. However, KYNA levels showed an increase in each cerebral region evaluated (Fig.

4B, ± 18, ± 58, ± and ± 17% for hippocampus, Author: Daniela Ramirez Ortega, Paulina Ovalle Rodríguez, Benjamín Pineda, Dinora F. González Esquivel, Luci. Your Brain on Heavy Metals: The Metals Most Frequently Associated with Depression. The metals most frequently associated with depression are lead, mercury, and cadmium, and they are commonly found in our environment.

We can trace the origins of these particular toxins to factories, dental work, welding equipment, cigarette smoke, and old. It is widely known that the degeneration of neural circuits is prominent in the brains of Alzheimer’s disease (AD) patients.

The reciprocal connectivity of the medial septum (MS) and hippocampus, which constitutes the septo-hippocampo-septal (SHS) loop, is known to be associated with learning and memory. Despite the importance of the reciprocal projections between the MS and hippocampus in Author: Sujin Kim, Yunkwon Nam, Yu-on Jeong, Hyun Ha Park, Seong-kyung Lee, Soo Jung Shin, Haram Jung, Byeon.

The rat hippocampal region is frequently studied in relation to learning and memory processes and brain diseases.

The region is complex, consisting of multiple subdivisions that are challenging to delineate anatomically. Published atlases of the rat brain typically lack the underlying histological criteria necessary to identify boundaries, and textbooks descriptions of the region are often Cited by: Stratum lucidum (str.

luc.) is one of the thinnest strata in the hippocampus and only found in the CA3 region. Mossy fibers from the dentate gyrus granule cells course through this stratum in CA3, though synapses from these fibers can be found in str.

g: Heavy metals. Heavy metals can produce health problems because of oxidative stress (Cd, Cr, Pb, As), neurological damage (Pb, Hg), DNA damage (As, Cr, Cd), changes in the metabolism of glucose (As) and calcium (Cd, Pb) and interfere with essential elements (Cd, Hg).

It is because of this that these metals have a teratogenic potential, which depends also on Cited by: Hippocampus, region of the brain that is associated primarily with name hippocampus is derived from the Greek hippokampus (hippos, meaning “horse,” and kampos, meaning “sea monster”), since the structure’s shape resembles that of a sea hippocampus, which is located in the inner (medial) region of the temporal lobe, forms part of the limbic system, which is Missing: Heavy metals.

cally, in the patients, the region of the hippocampus (defined as the fimbria, dentate gyrus, hippocampus proper, and subicu-lum) appeared markedly shrunken and atrophic (57% of normal size). In contrast, the area of the temporal lobe excluding the hippocampal region Missing: Heavy metals.

Title: Computational Models of the Hippocampal Region: Implications for Prediction of Risk for Alzheimers Disease in Non-demented Elderly VOLUME: 3 ISSUE: 3 Author(s):Mark A. Gluck, Catherine E. Myers, Michelle M. Nicolle and Sterling Johnson Affiliation:Center for Neuroscience, Rutgers University-Newark, University Avenue, Newark, NJ ,g: Heavy metals.

Gintonin is a newly discovered ingredient of ginseng and plays an exogenous ligand for G protein-coupled lysophosphatidic acid receptors. We previously showed that gintonin exhibits diverse effects from neurotransmitter release to improvement of Alzheimer’s disease-related cognitive dysfunctions.

However, previous studies did not show whether gintonin has protective effects against Author: Hyeon-Joong Kim, Sun-Hye Choi, Na-Eun Lee, Hee-Jung Cho, Hyewhon Rhim, Hyoung-Chun Kim, Sung-Hee Hwa.

In vivo treatment of rats with a single dose of the chelating agent diethyldithiocarbamate caused a reversible chelation of heavy metals in the hippocampus.

This effect was paralleled by a 3-fold increase in hippocampal content of CCK-8 and a smaller increase in the intermediate forms of CCK (CCK, CCK, CCK).

Diethyldithiocarbamate also decreased the spontaneous motility and aggressiveness. In the rat and guinea pig hippocampus, the staining pattern for enkephalin (by immunocytochemistry) and for zinc (by the Timm method) is congruent and confined to the mossy fiber system.

The stereospecific binding of 3H-enkephalinamide (2-D-AlaL-methionine) to. Elemental characterisation of the pyramidal neuron layer within the rat and mouse hippocampus which can be detected with histochemical methods.

43,44 However, the co-localisation of other metals within this hippocampal sub-region, such as Fe, Elemental characterisation of the pyramidal neuron layer within the rat and mouse hippocampus.

Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables : D Mn concentration in blood and hippocampus and Mn exposure affected the ability to learn and memory in mice To confirm the validity of the Mn model, we tested Mn levels in blood and hippocampal tissues by atomic fluorescence spectro-photometry in various groups of mice injected with the metal for 7 d.

The concentration of Mn in blood and in Cited by: analysis of the staining for the heavy metal zinc. Moving from lateral to medioventral, the first entity is the dorso-lateral region (DL) that can be subdivided into a dorsal component with dense kainate receptors and a ventral division that expresses 5-HT1A receptors.

The next area is the dorsomedial region (DM) that can be subdivided. Research Rundown: Mouse study to find link between MT-1 protein and Alzheimer’s-associated factors. Alzheimer’s Disease is a form of neurodegenerative disease thought to be caused by the formation of brain-lesioning plaques of amyloid-β oligomers and tangles of tau proteins accumlati.

The hippocampus is the part of the brain that is involved in forming, organizing, and storing memories. It is a limbic system structure that is particularly important in forming new memories and connecting emotions and senses, such as smell and sound, to hippocampus is a horseshoe shaped structure, with an arching band of nerve fibers (fornix) connecting the hippocampal structures Author: Regina Bailey.

Doctors also show off their lack of wit denying how toxicity from heavy metals, chemicals and radiation also affects their patients.

The weight of evidence based on the findings of wildlife biologists, toxicologists, and epidemiologists clearly indicates that the world’s populations are being exposed to a host of chemical contaminants and heavy metals. Zinc and Hippocampal Function I. Crawford and J.

Connor1 INTRODUCTION Zinc and Hippocampal Cytoarchitecture Considerable attention has been focused recently on the hippocampus as a brain region in which a relationship between a trace metal and neuronal function may be amenable to investiga-tion.

Maske () made the initial observation. In this study we intend to further characterize the roles of the antioxidant, anti-inflammatory, and heavy metal binding protein, metallothionein-1 (MT-1), by crossing Mt1 overexpressing mice with a well-known mouse model of AD, Tg mice, which express the human amyloid-β protein precursor (hAβPP) with the Swedish KN/ML mutations.

The hippocampal mossy fibers, by virtue of their high after application of each heavy metal in the presence or absence of the G q inhibitor. The R obtained in the presence of the inhibitor was trol for the number of cells in the region of in-terest. The images were assigned false color scales and superimposed with Adobe Photo-Cited by: Figure 6 shows that, after the primary cultured rat hippocampal neurons were treated with E 2 ( μM), Gen (2 μM) and Que (25 and 50 μM) for 24 h, there were significant increase in ERα protein but not ERβ protein.

DISCUSSION. In the present study, it has been demonstrated that quercetin can maintance cell viability of estrogen receptor positive neuronal cells in a certain dose range. In this chapter, the authors described the actuality of the investigations of neurocognitive dysfunctions in patients with iron deficiency.

In infants, the incidence of iron deficiency is 73%; the probability of its transition to iron deficiency anemia is very high. The development of myelin at an early age reduces the production of myelin, and the formation of g-aminobutyric acid worsens the Author: Elena Zhukovskaya, Alexander Karelin, Alexander Rumyantsev.

Haug FM: Heavy metals in the brain. A light microscope study of the rat with Timm's sulphide silver method. Methodological considerations and cytological and regional staining patterns. Adv Anat Embryol Cell Biol 1 – 71, Haug FM: Heavy metals in the brain.

A light microscope study of the rat with Timm's sulphide silver by: 20 Ways to Beat Alzheimer’s Disease. One of the fastest growing diseases in the industrial world is Alzheimer’s disease (AD). This is characterized by massive degeneration of the brain that causes disruptions in memory, cognition, personality that finally culminates with brain death.

Approximately, million Americans have Alzheimer’s and that number is expected to go up to 15 million. GST genotype and heavy metal metabolism have been studied and it was found that one form of gene readily metabolizes metals into non-toxic form and thus reduces the risk of toxicity [, ].

Children of mothers with GSTM1 and GSTT1 allele, prenatally exposed to pesticides are at greater risk of fetal growth restriction [ ].Cited by:   The Hippocampus as a Cognitive Map: the book Posted on Octo by jkubie A few weeks ago the Nobel Prize Committee announced that John O’Keefe, Edvard Moser and May-Britt Moser would be the recipients of the prize for Physiology and Medicine for their work in deciphering the code of neurons in the rat hippocampal g: Heavy metals.Encephalitis is an inflammation of the brain tissue.

The most common cause is viral infections. In rare cases it can be caused by bacteria or even g: Heavy metals.